Hopkins, M orcid.org/0000-0002-7655-0215, Gibbons, C, Caudwell, P et al. (5 more authors) (2014) The adaptive metabolic response to exercise-induced weight loss influences both energy expenditure and energy intake. European Journal of Clinical Nutrition, 68 (5). pp. 581-586. ISSN 0954-3007
Abstract
Background/objectives: A decline in resting energy expenditure (REE) beyond that predicted from changes in body composition has been noted following dietary-induced weight loss. However, it is unknown whether a compensatory downregulation in REE also accompanies exercise (EX)-induced weight loss, or whether this adaptive metabolic response influences energy intake (EI).
Subjects/methods: Thirty overweight and obese women (body mass index (BMI)=30.6±3.6 kg/m2) completed 12 weeks of supervised aerobic EX. Body composition, metabolism, EI and metabolic-related hormones were measured at baseline, week 6 and post intervention. The metabolic adaptation (MA), that is, difference between predicted and measured REE was also calculated post intervention (MApost), with REE predicted using a regression equation generated in an independent sample of 66 overweight and obese women (BMI=31.0±3.9 kg/m2).
Results: Although mean predicted and measured REE did not differ post intervention, 43% of participants experienced a greater-than-expected decline in REE (−102.9±77.5 kcal per day). MApost was associated with the change in leptin (r=0.47; P=0.04), and the change in resting fat (r=0.52; P=0.01) and carbohydrate oxidation (r=−0.44; P=0.02). Furthermore, MApost was also associated with the change in EI following EX (r=−0.44; P=0.01).
Conclusions: Marked variability existed in the adaptive metabolic response to EX. Importantly, those who experienced a downregulation in REE also experienced an upregulation in EI, indicating that the adaptive metabolic response to EX influences both physiological and behavioural components of energy balance.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2014 Macmillan Publishers Limited. This is an author produced version of a paper published in European Journal of Clinical Nutrition. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | exercise-induced weight loss; energy intake; resting energy expenditure; leptin |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) > FSN Nutrition and Public Health (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Psychology (Leeds) |
Funding Information: | Funder Grant number BBSRC BBS/B/05079 |
Depositing User: | Symplectic Publications |
Date Deposited: | 07 Feb 2019 15:46 |
Last Modified: | 25 Jun 2023 21:38 |
Status: | Published |
Publisher: | Nature Publishing Group |
Identification Number: | 10.1038/ejcn.2013.277 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:139869 |
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