Second round results from the Manchester ‘Lung Health Check’ community-based targeted lung cancer screening pilot

Abstract

We report results from the second annual screening round (T1) of Manchester’s ‘Lung Health Check’ pilot of community-based lung cancer screening in deprived areas (undertaken June to August 2017). Screening adherence was 90% (n=1194/1323): 92% of CT scans were classified negative, 6% indeterminate and 2.5% positive; there were no interval cancers. Lung cancer incidence was 1.6% (n=19), 79% stage I, treatments included surgery (42%, n=9), stereotactic ablative radiotherapy (26%, n=5) and radical radiotherapy (5%, n=1). False-positive rate was 34.5% (n=10/29), representing 0.8% of T1 participants (n=10/1194). Targeted community-based lung cancer screening promotes high screening adherence and detects high rates of early stage lung cancer.

Metadata

Item Type:	Article
Authors/Creators:	Crosbie, PA Balata, H Evison, M Atack, M Bayliss- Brideaux, V Colligan, D Deurden, R Eaglesfield, J Edwards, T Elton, P Foster, J Greaves, M Hayler, G Higgins, C Howells, J Irion, K Karunaratne, D Kelly, J King, Z Lyons, J Manson, S Mellor, S Miller, D Myerscough, A Newton, T O’Leary, M Pearson, R Pickford, J Sawyer, R Screaton, NJ Sharman, A Simmons, M Smith, E Taylor, B Taylor, S Walsham, A Watts, A Whittaker, J Yarnell, L Threlfall, A Barber, PV Tonge, J https://orcid.org/0000-0001-9687-9184 Booton, R
Copyright, Publisher and Additional Information:	© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
Keywords:	Lung cancer; Screening
Dates:	Published: 13 June 2019 Published (online): 12 November 2018 Accepted: 22 October 2018
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds)
Depositing User:	Symplectic Publications
Date Deposited:	05 Dec 2018 10:54
Last Modified:	25 Jun 2023 21:37
Status:	Published
Publisher:	BMJ Publishing Group
Identification Number:	10.1136/thoraxjnl-2018-212547
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:139546

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Second round results from the Manchester ‘Lung Health Check’ community-based targeted lung cancer screening pilot

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