Manske, SL, Brunet, SC, Finzel, S et al. (4 more authors) (2019) The SPECTRA Collaboration OMERACT Working Group: Criterion Validity of Joint Space Outcomes with High Resolution Peripheral Quantitative Computed Tomography. Journal of Rheumatology, 46 (10). jrheum.180870. pp. 1369-1373. ISSN 0315-162X
Abstract
Objective: We assessed construct validity of high-resolution peripheral quantitative computed tomography (HR-pQCT) joint space outcomes by comparison with radiographs in patients with rheumatoid arthritis.
Methods: In 43 patients, quantitative, volumetric, HR-pQCT measurements were compared with ordinal Sharp/van der Heijde scoring (SvdH) in the 2nd and 3rd metacarpophalangeal joints.
Results: Generalized estimating equations showed that joint space minimum, SD, and asymmetry by HR-pQCT were associated with SvdH scores (p < 0.05). There was a considerable range in HR-pQCT measurements at SvdH equal to 0.
Conclusion: HR-pQCT demonstrated construct validity outcomes and provides improved 3-D visualization of joint space.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Editors: |
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Copyright, Publisher and Additional Information: | © 2019 The Journal of Rheumatology. This is a pre-copyediting, author-produced PDF of an article accepted for publication in The Journal of Rheumatology following peer review. The definitive publisher-authenticated version is available online at: https://doi.org/10.3899/jrheum.180870. |
Keywords: | rheumatoid arthritis, outcome assessment, radiography, computed tomography, metacarpophalangeal joint |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Musculoskeletal Medicine & Imaging (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 19 Nov 2018 14:49 |
Last Modified: | 15 Jan 2020 01:39 |
Status: | Published |
Publisher: | Journal of Rheumatology |
Identification Number: | 10.3899/jrheum.180870 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:138752 |