Rossi, S, Lassila, T orcid.org/0000-0001-8947-1447, Ruiz-Baier, R et al. (2 more authors) (2014) Thermodynamically consistent orthotropic activation model capturing ventricular systolic wall thickening in cardiac electromechanics. European Journal of Mechanics - A/Solids, 48. pp. 129-142. ISSN 0997-7538
Abstract
The complex phenomena underlying mechanical contraction of cardiac cells and their influence in the dynamics of ventricular contraction are extremely important in understanding the overall function of the heart. In this paper we generalize previous contributions on the active strain formulation and propose a new model for the excitation-contraction coupling process. We derive an evolution equation for the active fiber contraction based on configurational forces, which is thermodynamically consistent. Geometrically, we link microscopic and macroscopic deformations giving rise to an orthotropic contraction mechanism that is able to represent physiologically correct thickening of the ventricular wall. A series of numerical tests highlights the importance of considering orthotropic mechanical activation in the heart and illustrates the main features of the proposed model.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2013 Elsevier Masson SAS. All rights reserved. This is an author produced version of a paper published in European Journal of Mechanics - A/Solids. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Cardiac electromechanics; Configurational forces; Active strain |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Computing (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 08 Nov 2018 10:01 |
Last Modified: | 08 Nov 2018 10:01 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.euromechsol.2013.10.009 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:137455 |