Easthall, C orcid.org/0000-0002-9810-3870, Taylor, N and Bhattacharya, D (2019) Barriers to medication adherence in patients prescribed medicines for the prevention of cardiovascular disease: a conceptual framework. International Journal of Pharmacy Practice, 27 (3). pp. 223-231. ISSN 0961-7671
Abstract
Objectives
To identify barriers to medication adherence in patients prescribed medicines for the prevention of cardiovascular disease and map these to the Theoretical Domains Framework (TDF), to produce a conceptual framework for developing a questionnaire‐based medication adherence tool.
Methods
A scoping review of barriers to medication adherence in long‐term conditions was conducted to generate an initial pool of barriers. After preliminary mapping to the TDF, these barriers were presented to two focus groups of patients prescribed medicines for the prevention of cardiovascular disease (n = 14) to stimulate discussion. The group discussions enabled the patients’ interpretations of the adherence barriers to be determined, provided validity from the patient perspective and identified additional barriers unrepresented in the scoping review.
Key findings
The preliminary pool of adherence barriers was identified from 47 studies across a range of long‐term conditions. The majority of TDF domains were represented by these literature‐identified barriers except ‘social/professional role and identity’ and ‘behavioural regulation’. Barrier mapping was largely endorsed by focus group participants, who also contributed additional barriers, including those relating to not having a ‘system’ in place for managing their medicines and the negative emotions evoked by medicine taking.
Conclusion
The TDF enabled full exploration of adherence barriers including those relating to emotions which have received limited attention in the literature. This work has provided a conceptual framework for developing a questionnaire to identify an individual's adherence barriers which may then be coupled with appropriate behaviour change techniques to deliver a theory‐based intervention tailored for individual need.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018 Royal Pharmaceutical Society. This is the peer reviewed version of the following article: Easthall, C , Taylor, N and Bhattacharya, D (2019) Barriers to medication adherence in patients prescribed medicines for the prevention of cardiovascular disease: a conceptual framework. International Journal of Pharmacy Practice, 27 (3). pp. 223-231. ISSN 0961-7671, which has been published in final form at https://doi.org/10.1111/ijpp.12491. This article may be used for noncommercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Focus group; IMAB-Q; Questionnaire; Scoping review; Thoretical Domains Framework (TDF) |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Healthcare (Leeds) > Pharmacy (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 09 Oct 2018 15:07 |
Last Modified: | 03 Oct 2019 00:38 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1111/ijpp.12491 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:136881 |