Kinoshita, M, Lin, Y, Dai, I et al. (5 more authors) (2018) Energy landscape of polymorphic amyloid generation of β2-microglobulin revealed by calorimetry. Chemical Communications, 54 (57). pp. 7995-7998. ISSN 1359-7345
Abstract
Understanding of amyloid aggregation in terms of thermodynamics and kinetics is still limited. We herein examined the mechanism of β2-microglobulin amyloidogenesis using our unique method of isothermal titration calorimetry-based thermodynamic/kinetic measurements, and revealed the energy landscape of polymorphic amyloidogenesis under biological environment-mimicking conditions including shear forces and crowding effects.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 16 Jul 2018 11:01 |
Last Modified: | 16 Jul 2018 11:01 |
Status: | Published |
Publisher: | Royal Society of Chemistry |
Identification Number: | 10.1039/c8cc02718h |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:133298 |
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