Abhari, RE, Mouthuy, PA, Vernet, A et al. (3 more authors) (2018) Using an industrial braiding machine to upscale the production and modulate the design of electrospun medical yarns. Polymer Testing, 69. pp. 188-198. ISSN 0142-9418
Abstract
While electrospun multifilaments have shown initial promise as medical yarns, their development has been restricted to short sections of hand-braided yarns. Integrating electrospun material into existing industrial braiding production lines would enable the modulation of yarn properties and an increased production rate to meet the demand for clinical trials. In this study, we used an industrial braiding machine to manufacture multifilament polydioxanone yarns with various filament numbers and carrier arrangements. The resulting yarns were characterized by mercury porosimetry, mechanical and pull through testing and compared to clinically used braided Vicryl and monofilament polydioxanone (PDS) sutures. Electrospun yarns were significantly more porous (67%) compared with Vicryl (28%) and PDS sutures (0%), and possessed the classic toe region reminiscent of native tissue. Pull through testing revealed that the structural configuration of electrospun yarns allowed for more energy dissipation. These findings suggest that upscaling the production of braided yarns is critical for designing medical yarns with required properties for clinical applications.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Keywords: | Yarn design; Braiding; Electrospinning; Medical Yarn; Suture |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) |
Depositing User: | Symplectic Publications |
Date Deposited: | 04 Jul 2018 10:03 |
Last Modified: | 04 Jul 2018 10:03 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.polymertesting.2018.05.014 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:132884 |