Recent Asian origin of chytrid fungi causing global amphibian declines

Abstract

Globalized infectious diseases are causing species declines worldwide, but their source often remains elusive. We used whole-genome sequencing to solve the spatiotemporal origins of the most devastating panzootic to date, caused by the fungus Batrachochytrium dendrobatidis, a proximate driver of global amphibian declines. We traced the source of B. dendrobatidis to the Korean peninsula, where one lineage, BdASIA-1, exhibits the genetic hallmarks of an ancestral population that seeded the panzootic. We date the emergence of this pathogen to the early 20th century, coinciding with the global expansion of commercial trade in amphibians, and we show that intercontinental transmission is ongoing. Our findings point to East Asia as a geographic hotspot for B. dendrobatidis biodiversity and the original source of these lineages that now parasitize amphibians worldwide.

Metadata

Item Type:	Article
Authors/Creators:	O’Hanlon, Simon J. Rieux, Adrien Farrer, Rhys A. Rosa, Gonçalo M. Waldman, Bruce Bataille, Arnaud Kosch, Tiffany A. Murray, Kris A. Brankovics, Balázs Fumagalli, Matteo Martin, Michael D. Wales, Nathan https://orcid.org/0000-0003-0359-8450 Alvarado-Rybak, Mario Bates, Kieran A. Berger, Lee Böll, Susanne Brookes, Lola Clare, Frances Courtois, Elodie A. Cunningham, Andrew A. Doherty-Bone, Thomas M. Ghosh, Pria Gower, David J. Hintz, William E. Höglund, Jacob Jenkinson, Thomas S. Lin, Chun Fu Laurila, Anssi Loyau, Adeline Martel, An Meurling, Sara Miaud, Claude Minting, Pete Pasmans, Frank Schmeller, Dirk S. Schmidt, Benedikt R. Shelton, Jennifer M.G. Skerratt, Lee F. Smith, Freya Soto-Azat, Claudio Spagnoletti, Matteo Tessa, Giulia Toledo, Luís Felipe Valenzuela-Sánchez, Andrés Verster, Ruhan Vörös, Judit Webb, Rebecca J. Wierzbicki, Claudia Wombwell, Emma Zamudio, Kelly R. Aanensen, David M. James, Timothy Y. Thomas, M. (mbt507@york.ac.uk) Weldon, Ché Bosch, Jaime Balloux, François Garner, Trenton W.J. Fisher, Matthew C.
Copyright, Publisher and Additional Information:	This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details
Dates:	Accepted: 1 April 2018 Published: 11 May 2018
Institution:	The University of York
Academic Units:	The University of York > Faculty of Arts and Humanities (York) > Archaeology (York) The University of York > Faculty of Sciences (York) > Physics (York)
Depositing User:	Pure (York)
Date Deposited:	28 Jun 2018 11:10
Last Modified:	09 Apr 2025 23:17
Published Version:	https://doi.org/10.1126/science.aar1965
Status:	Published
Refereed:	Yes
Identification Number:	10.1126/science.aar1965
Related URLs:	http://www.scopus.com/inward/record.url?...
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:132755

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Recent Asian origin of chytrid fungi causing global amphibian declines

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