Friend, A orcid.org/0000-0001-9864-5605, Rubagumya, F and Cartledge, P (2018) Global Health Journal Club: Is Honey Effective as a Treatment for Chemotherapy-induced Mucositis in Paediatric Oncology Patients? Journal of Tropical Pediatrics, 64 (2). pp. 162-168. ISSN 0142-6338
Abstract
Oral mucositis (OM) is an inflammatory response of mucosal epithelium to the cytotoxic effects of chemotherapy and radiotherapy causing severe oral pain and ulceration, which may complicate the management of cancer. The Mucositis Prevention Guideline Development Group has developed an international guideline for the prevention of mucositis in children receiving treatment for cancer or undergoing haematopoietic stem cell transplantation. Evidence-based preventative strategies include cryotherapy, low-level light therapy and keratinocyte growth factor. However, these strategies are often not available in resource-poor settings. There is some evidence that honey may be a suitable treatment for OM in adult patients. We performed a literature search of 11 databases to find papers exploring the use of honey to treat chemotherapy-associated mucositis in paediatric oncology patients. We found four papers, which provide Grade C evidence that honey is effective as a preventative and therapeutic measure for OM in paediatric oncology patients.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author, 2017. Published by Oxford University Press. This is an author produced version of a paper published in Journal of Tropical Pediatrics. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | mucositis, honey, oncology, paediatrics, developing countries, global health |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Epidemiology and Biostatistics (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 22 Jun 2018 09:25 |
Last Modified: | 30 Nov 2018 01:39 |
Status: | Published |
Publisher: | Oxford University Press |
Identification Number: | 10.1093/tropej/fmx092 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:132330 |