Jefferson, Laura Anne orcid.org/0000-0003-2139-3555, Fairhurst, Caroline Marie orcid.org/0000-0003-0547-462X, Brealey, Stephen Derek orcid.org/0000-0001-9749-7014 et al. (9 more authors) (2018) Remote or on-site visits were feasible for the initial setup meetings with hospitals in a multicenter surgical trial:an embedded randomized trial. Journal of Clinical Epidemiology. pp. 13-21. ISSN 0895-4356
Abstract
Objectives To investigate the effects, costs and feasibility of providing on-site compared with remote meetings to set-up hospital sites in a multi-centre, surgical randomised controlled trial. Study Design and Setting Hospitals were randomised to receive the initial trial set-up meetings on-site (i.e. face-toface) or remotely (i.e. via teleconference). Data were collected on site set-up, recruitment, follow-up and costs for the two methods. The hospital staff experience of trial set-up was also surveyed. Results Thirty-nine sites were randomised and 33 sites set-up to recruit (19 on-site and 14 remote). For sites randomised to an on-site meeting compared with remote meeting respectively, the time from first contact to first recruit was a median of 246 days [interquartile range (IQR) 196 to 346] vs 212 days [IQR 154 to 266], mean recruitment was 10 participants [median 10, IQR 2 to 17] vs 11 participants [median 6, IQR 5 to 23] and participant follow-up at 12 months was 81% vs 82%. Sites allocated to an initial on-site visit cost on average 289.83 more to set-up. Conclusion Remote or on-site visits are feasible for the initial set-up meetings with hospitals in a multicentre surgical trial. This embedded trial should be replicated to improve generalisability and increase statistical power using meta-analysis. ISRCTN78899574. Keywords: Study Within a Trial; Randomised Controlled Trial; Recruitment; Response rate; Costs; Feasibility A running title: Remote and on-site visits were feasible for the initial set-up meetings with hospitals in a multi-centre surgical trial
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018 Elsevier Inc.This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. |
Keywords: | Costs,Feasibility,Randomized controlled trial,Recruitment,Response rate,Study within a trial |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Health Sciences (York) |
Depositing User: | Pure (York) |
Date Deposited: | 24 May 2018 09:20 |
Last Modified: | 08 Feb 2025 00:28 |
Published Version: | https://doi.org/10.1016/j.jclinepi.2018.04.011 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1016/j.jclinepi.2018.04.011 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:131295 |
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Licence: CC-BY-NC-ND 2.5