Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)

Williamson, Douglas S., Smith, Garrick P., Acheson-Dossang, Pamela et al. (20 more authors) (2017) Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1). JOURNAL OF MEDICINAL CHEMISTRY. pp. 8945-8962. ISSN 0022-2623

Metadata

Item Type: Article
Authors/Creators:
  • Williamson, Douglas S.
  • Smith, Garrick P.
  • Acheson-Dossang, Pamela
  • Bedford, Simon T.
  • Chell, Victoria
  • Chen, I-Jen
  • Daechsel, Justus C. A.
  • Daniels, Zoe
  • David, Laurent
  • Dokurno, Pawel
  • Hentzer, Morten
  • Herzig, Martin C.
  • Hubbard, Roderick E. ORCID logo https://orcid.org/0000-0002-8233-7461
  • Moore, Jonathan D.
  • Murray, James B.
  • Newland, Samantha
  • Ray, Stuart C.
  • Shaw, Terry
  • Surgenor, Allan E.
  • Terry, Lindsey
  • Thirstrup, Kenneth
  • Wang, Yikang
  • Christensen, Kenneth V.
Copyright, Publisher and Additional Information:

© 2017 American Chemical Society. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details
Dates:
  • Published: 12 October 2017
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Chemistry (York)
Depositing User: Pure (York)
Date Deposited: 08 May 2018 15:50
Last Modified: 02 Apr 2025 23:12
Published Version: https://doi.org/10.1021/acs.jmedchem.7b01186
Status: Published
Refereed: Yes
Identification Number: 10.1021/acs.jmedchem.7b01186
Open Archives Initiative ID (OAI ID):

Download

Accepted Version

Filename: Pyrrolopyridines_J_Med_Chem.pdf

Description: Pyrrolopyridines_J_Med_Chem

CLICK TO DOWNLOAD [thumbnail of Pyrrolopyridines_J_Med_Chem]

Export

Statistics


CORE (COnnecting REpositories)