Transcription factors in eukaryotic cells can functionally regulate gene expression by acting in oligomeric assemblies formed from an intrinsically disordered protein phase transition enabled by molecular crowding

Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2018) Transcription factors in eukaryotic cells can functionally regulate gene expression by acting in oligomeric assemblies formed from an intrinsically disordered protein phase transition enabled by molecular crowding. Transcription. pp. 298-306.

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Item Type: Article
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Funding Information: Supported by the Biological Physical Sciences Institute, Royal Society, MRC (grant MR/K01580X/1), BBSRC (grant BB/ N006453/1), Swedish Research Council and European Commission via Marie Curie-Network for Initial training ISOLATE (Grant agreement nr: 289995) and the Marie Curie Alumni Association.
Keywords: Circular Dichroism,DNA-Binding Proteins/genetics,Gene Expression Regulation, Fungal,Green Fluorescent Proteins/genetics,Microscopy, Fluorescence/methods,Nuclear Envelope/metabolism,Nuclear Pore/metabolism,Phase Transition,Phosphorylation,Promoter Regions, Genetic,Proteomics,Repressor Proteins/genetics,Saccharomyces cerevisiae Proteins/genetics,Saccharomyces cerevisiae/genetics,Single Molecule Imaging/methods,Transcription Factors/genetics
Dates:
  • Published: 9 August 2018
  • Published (online): 12 June 2018
  • Accepted: 3 May 2018
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Biology (York)
The University of York > Faculty of Sciences (York) > Physics (York)
Depositing User: Pure (York)
Date Deposited: 04 May 2018 10:30
Last Modified: 16 Oct 2024 14:42
Published Version: https://doi.org/10.1080/21541264.2018.1475806
Status: Published
Refereed: Yes
Identification Number: 10.1080/21541264.2018.1475806
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