du Plessis d’Argentre, A., Perry, S., Iwata, Y. et al. (7 more authors) (2018) Programmable medicine: Autonomous, ingestible, deployable hydrogel patch and plug for stomach ulcer therapy. In: Proceedings of 2018 IEEE International Conference on Robotics and Automation (ICRA). IEEE International Conference on Robotics and Automation, 21-25 May 2018, Brisbane, QLD, Australia. IEEE , pp. 1511-1518. ISBN 978-1-5386-3081-5
Abstract
Gastric ulcer is a chronic and complex (and often complete) erosion of the stomach wall that happens as a complication of a previous chronic, inflammatory process. It represents a catastrophic situation in which the patient is critical and its conditions need to be treated fast. This study presents a remotely navigatable and deployable ingestible patch and plug for gastric ulcer treatment. The patch/plug structure is made of agarose hydrogel that can change rigidity through hydration and dehydration. When dehydrated, it is rigid and can maintain a folded configuration so it can be ingested as a “pill”. This can be guided to the targeted location by a magnetic field, and be deployed instantly by hydration, namely by supplying water from the mouth. Due to the deployable origami design, it exhibits an expansion of 10 times its initial surface area, making the device suitable for the use of dressing a surface as a patch, and filling a hole as a plug.
Metadata
Item Type: | Proceedings Paper |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works. Reproduced in accordance with the publisher's self-archiving policy. |
Keywords: | Plugs; Stomach; Navigation; Shape; Fabrication; Robot sensing systems |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Automatic Control and Systems Engineering (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 22 Mar 2018 16:16 |
Last Modified: | 01 Nov 2018 15:23 |
Published Version: | https://doi.org/10.1109/ICRA.2018.8460615 |
Status: | Published |
Publisher: | IEEE |
Refereed: | Yes |
Identification Number: | 10.1109/ICRA.2018.8460615 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:128853 |