Vatansever, Deniz orcid.org/0000-0002-2494-9945, Manktelow, Anne E, Sahakian, Barbara J et al. (2 more authors) (2018) Default Mode Network Engagement Beyond Self-Referential Internal Mentation. Brain Connectivity. ISSN 2158-0022
Abstract
The default mode network (DMN) is typically associated with off-task internal mentation, or with goal-oriented tasks that require self-referential processing such as autobiographical planning. However, recent reports suggest a broader involvement of the DMN in higher cognitive processing. In line with this view, we report global connectivity changes centred on the main DMN hubs of precuneus and posterior cingulate cortex during an fMRI-based visuospatial version of the Tower of London planning task. Importantly, functional connectivity of these regions and the left caudate shows a significant relationship with faster reaction time to correct responses only during the high-demand planning condition, thus offering further evidence for the DMN's engagement during visuospatial planning. The results of this study not only provide robust evidence against the widely held notion of DMN disengagement during goal-oriented, attention-demanding, externally-directed tasks, but also support its involvement in a broader cognitive context with a memory-related role that extends beyond self-referential, internally-directed mentation.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) |
Depositing User: | Pure (York) |
Date Deposited: | 05 Mar 2018 11:10 |
Last Modified: | 02 Apr 2025 23:11 |
Published Version: | https://doi.org/10.1089/brain.2017.0489 |
Status: | Published online |
Refereed: | Yes |
Identification Number: | 10.1089/brain.2017.0489 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:128186 |
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