Cole, Eleanor Jane, Barraclough, Nicholas Edward orcid.org/0000-0003-2818-326X and Enticott, Peter G. (2018) Investigating mirror system (MS) activity in adults with ASD when inferring others' intentions using both TMS and EEG. Journal of Autism and Developmental Disorders. ISSN 0162-3257
Abstract
ASD is associated with mentalizing deficits that may correspond with atypical mirror system (MS) activation. We investigated MS activity in adults with and without ASD when inferring others’ intentions using TMS-induced motor evoked potentials (MEPs) and mu suppression measured by EEG. Autistic traits were measured for all participants. Our EEG data show, high levels of autistic traits predicted reduced right mu (8–10 Hz) suppression when mentalizing. Higher left mu (8–10 Hz) suppression was associated with superior mentalizing performances. Eye-tracking and TMS data showed no differences associated with autistic traits. Our data suggest ASD is associated with reduced right MS activity when mentalizing, TMS-induced MEPs and mu suppression measure different aspects of MS functioning and the MS is directly involved in inferring intentions.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2018. |
Keywords: | AUTISM,ASD,MIRROR NEURONS,mentalizing,TMS,EEG,Electroencephalography (EEG),TRANSCRANIAL MAGNETIC STIMULATION,INTENTIONS,AUTISM SPECTRUM DISORDERS,PERCEPTION |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) |
Depositing User: | Pure (York) |
Date Deposited: | 28 Feb 2018 14:30 |
Last Modified: | 16 Oct 2024 14:30 |
Status: | Published online |
Refereed: | Yes |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:128037 |