Knight, Emma R., Carter, Laura Jayne and McLaughlin, Michael J. (2018) Bioaccumulation, Uptake, and Toxicity of Carbamazepine in Soil–Plant Systems. Environmental Toxicology and Chemistry. ISSN 1552-8618
Abstract
Since the detection of active pharmaceutical ingredients (APIs) in various environmental media, research has explored the potential uptake and toxicity of these chemicals to species inhabiting these matrices. Specifically, pharmaceuticals, including the antiepileptic API carbamazepine (CBZ), are taken up from soil by a range of plants. Many short-term studies have also suggested that certain APIs induce toxicity in plants. However, the effects of APIs on fruiting plants remain relatively unexplored. The present study investigated the uptake, bioaccumulation, and toxicity of CBZ in Cucurbita pepo (zucchini) from seed to full maturity across a range of CBZ exposure concentrations in soil (0.1–20 mg/kg). Results of biomass, chlorophyll, starch and total nitrogen (N) concentration in C. pepo indicated toxicity at soil concentrations of 10 mg/kg. There were clear visual indications of increasing toxicity on leaves, including chlorosis and necrosis, from soil concentrations of 1 up to 20 mg/kg. The present study also revealed novel insights into the effect of CBZ accumulation on C. pepo fruiting: female C. pepo flowers were unable to set fruit when leaf concentrations were 14 mg/kg. These findings may have implications for future agricultural productivity in areas where reclaimed wastewater containing APIs is a source of irrigation. Detectable CBZ concentrations were found in edible C. pepo fruit, indicating the possibility of trophic transfer
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | ©2017 SETAC. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Environment and Geography (York) |
Depositing User: | Pure (York) |
Date Deposited: | 12 Feb 2018 16:50 |
Last Modified: | 16 Oct 2024 14:27 |
Published Version: | https://doi.org/10.1002/etc.4053 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1002/etc.4053 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:127391 |
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