Benjamin, Alex Victoria, Wailes-Newson, Kirstie Holly, Ma-Wyatt, Anna et al. (2 more authors) (2018) The effect of locomotion on early visual contrast processing in humans. Journal of neuroscience. pp. 3050-3059. ISSN 1529-2401
Abstract
Most of our knowledge about vision comes from experiments in which stimuli are presented to immobile human subjects or animals. In the case of human subjects, movement during psychophysical, electrophysiological or neuroimaging experiments is considered to be a source of noise to be eliminated. Animals used in visual neuroscience experiments are typically restrained and, in many cases, anaesthetized. In reality however, vision is often used to guide the motion of awake, ambulating organisms. Recent work in mice has shown that locomotion elevates visual neuronal response amplitudes (Erisken et al., 2014; Fu et al., 2014; Lee et al., 2014; Mineault et al., 2016; Niell and Stryker, 2010) and reduces long-range gain control (Ayaz et al., 2013). Here we use both psychophysics and steady-state electrophysiology to ask whether similar effects of locomotion on early visual processing can be measured in humans. Our psychophysical results show that brisk walking has little effect on subjects’ ability to detect briefly-presented contrast changes and that co-oriented flankers are, if anything, more effective masks when subjects are walking. Our electrophysiological data were consistent with the psychophysics, indicating no increase in stimulus-driven neuronal responses whilst walking and no reduction in surround suppression. In summary we find evidence that early contrast processing is altered by locomotion in humans but in a manner that differs from that reported in mice. The effects of locomotion on very low-level visual processing may differ on a species-by-species basis and may reflect important differences in the levels of arousal associated with locomotion.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018, Benjamin, Wailes-Newson et al. |
Keywords: | arousal,gain control,locomotion,murine models,SSVEP,Locomotion,Murine models,Arousal,Gain control,Locomotion/physiology,Humans,Male,Young Adult,Walking/physiology,Adult,Female,Contrast Sensitivity/physiology |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) > York Neuroimaging Centre The University of York > Faculty of Sciences (York) > Psychology (York) |
Depositing User: | Pure (York) |
Date Deposited: | 22 Jan 2018 13:50 |
Last Modified: | 08 Feb 2025 00:26 |
Published Version: | https://doi.org/10.1523/JNEUROSCI.1428-17.2017 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1523/JNEUROSCI.1428-17.2017 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:126452 |
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