Campo Rodrigo, Ana, Laurini, Erik, Vieira, Vania Margarida Pinto et al. (2 more authors) (2017) Effect of buffer at nanoscale molecular recognition interfaces - electrostatic binding of biological polyanions. Chemical communications. pp. 11580-11583. ISSN 1364-548X
Abstract
We investigate the impact of an over-looked component on molecular recognition in water–buffer. The binding of a cationic dye to biological polyanion heparin is shown by isothermal calorimetry to depend on buffer (Tris–HCl > HEPES > PBS). The heparin binding of self-assembled multivalent (SAMul) cationic micelles is even more buffer dependent. Multivalent electrostatic molecular recognition is buffer dependent as a result of competitive interactions between the cationic binding interface and anions present in the buffer.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 09 Nov 2017 14:19 |
Last Modified: | 21 Oct 2024 23:53 |
Status: | Published |
Refereed: | Yes |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:123819 |
Download
Filename: Ana_Buffer_Chem_Comm_2017.pdf
Description: Ana Buffer Chem Comm 2017