Åkerbladh, L, Chow, SY orcid.org/0000-0002-3600-0497, Odell, LR et al. (1 more author) (2017) Cover Profile: Synthesis of 4H-Benzo[e][1,3]oxazin-4-ones by a Carbonylation–Cyclization Domino Reaction of ortho-Halophenols and Cyanamide. Wiley Open Access, ChemistryOpen.
Abstract
Invited for this month′s cover are researchers from the Division of Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry, Uppsala University (Sweden). The research interests in the group span areas such as enzyme inhibitors, new antibiotics, angiotensin II AT2R ligands, PET tracers, palladium catalysis, heterocycle synthesis, and the development of novel multicomponent reactions. In particular, sequential carbonylation and cyclization appeal to us as a convenient and straightforward synthetic route for the synthesis of heterocycles. The cover picture shows how carbon monoxide gas is diffused over a bridge, in the two-chamber system set-up used in this work, to take part in the catalytic cycle, and be incorporated into the heterocyclic core by a carbonylation/cyclization domino reaction to yield 4H-benzo[e][1,3]oxazin-4-ones. For more details, see the full text of the Full Paper at 10.1002/open.201700130.
Metadata
Item Type: | Other |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 11 Oct 2017 11:39 |
Last Modified: | 06 Mar 2018 15:30 |
Status: | Published |
Publisher: | Wiley Open Access |
Identification Number: | 10.1002/open.201700145 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:122320 |