Huang, DB, Duncan, LR, Flamm, RK et al. (5 more authors) (2018) The Effect of Pulmonary Surfactant on the In Vitro Activity of Iclaprim Against Common Respiratory Bacterial Pathogens. Diagnostic Microbiology and Infectious Disease, 90 (1). pp. 64-66. ISSN 0732-8893
Abstract
The in vitro antimicrobial activity of iclaprim, a novel diaminopyrimidine, against common respiratory bacteria remained unchanged in the presence of pulmonary surfactant (Survanta®) at concentrations that greatly antagonized the antimicrobial activity of daptomycin. These results indicate that iclaprim could be a potential treatment for pneumonia caused by susceptible and multidrug resistant bacteria.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017 Elsevier Inc. This is an author produced version of a paper published in Diagnostic Microbiology and Infectious Disease. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | iclaprim; surfactant; pneumonia; in vitro |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Molecular Gastroenterology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 21 Sep 2017 09:18 |
Last Modified: | 20 Sep 2018 00:38 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.diagmicrobio.2017.09.011 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:121525 |