Riazi, S, Kraeva, N and Hopkins, PM orcid.org/0000-0002-8127-1739 (2018) Malignant Hyperthermia in the Post-Genomics Era: New Perspectives on an Old Concept. Anesthesiology, 128. pp. 168-180. ISSN 0003-3022
Abstract
This article reviews advancements in the genetics of malignant hyperthermia, new technologies and approaches for its diagnosis, and the existing limitations of genetic testing for malignant hyperthermia. It also reviews the various RYR1-related disorders and phenotypes, such as myopathies, exertional rhabdomyolysis, and bleeding disorders, and examines the connection between these disorders and malignant hyperthermia.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017, the American Society of Anesthesiologists, Inc. Wolters Kluwer Health, Inc. This is an author produced version of a paper published in Anesthesiology. Uploaded in accordance with the publisher's self-archiving policy. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Inst of Biomed & Clin Sciences (LIBACS) (Leeds) > Trans Anaesthetics & Surgical Sciences (Leeds) |
Funding Information: | Funder Grant number National Institute of Health - DELETED Not Known |
Depositing User: | Symplectic Publications |
Date Deposited: | 18 Sep 2017 14:52 |
Last Modified: | 14 Sep 2018 00:38 |
Status: | Published |
Publisher: | Lippincott, Williams & Wilkins |
Identification Number: | 10.1097/ALN.0000000000001878 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:121269 |