Maizels, Rick M and Hewitson, James P orcid.org/0000-0002-3265-6763 (2016) Myeloid Cell Phenotypes in Susceptibility and Resistance to Helminth Parasite Infections. Microbiology spectrum. ISSN 2165-0497
Abstract
Many major tropical diseases are caused by long-lived helminth parasites that are able to survive by modulation of the host immune system, including the innate compartment of myeloid cells. In particular, dendritic cells and macrophages show markedly altered phenotypes during parasite infections. In addition, many specialized subsets such as eosinophils and basophils expand dramatically in response to these pathogens. The changes in phenotype and function, and their effects on both immunity to infection and reactivity to bystander antigens such as allergens, are discussed.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2016 American Society for Microbiology. Uploaded with permission of the publisher/copyright holder. Further copying may not be permitted; contact the publisher for details |
Keywords: | Journal Article |
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Centre for Immunology and Infection (CII) (York) |
Depositing User: | Pure (York) |
Date Deposited: | 12 Jul 2017 08:45 |
Last Modified: | 26 Nov 2024 00:34 |
Published Version: | https://doi.org/10.1128/microbiolspec.MCHD-0043-20... |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1128/microbiolspec.MCHD-0043-2016 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:118962 |