Holch, P, Warrington, L orcid.org/0000-0002-8389-6134, Bamforth, LCA et al. (9 more authors) (2017) Development of an integrated electronic platform for patient self-report and management of adverse events during cancer treatment. Annals of Oncology, 28 (9). mdx317. pp. 2305-2311. ISSN 0923-7534
Abstract
Background: Significant adverse events (AE) during cancer therapy disrupt treatment and escalate to emergency admissions. Approaches to improve the timeliness and accuracy of AE reporting may improve safety and reduce health service costs. Reporting: AE via Patient Reported Outcomes (PROs), can improve clinician-patient communication and making data available to clinicians in ‘real time’ using electronic PROs (ePROs) could potentially transform clinical practice by providing easily-accessible records to guide treatment decisions. This manuscript describes the development of eRAPID (electronic patient self-Reporting of Adverse-events: Patient Information and aDvice) is a National Institute for Health Research (NIHR) funded programme,a system for patients to self-report and manage AE online during and after cancer treatment. Materials and methods: A multi-disciplinary team of IT experts, staff and patients developed using agile principles a secure web application interface (QStore) between an existing online questionnaire builder (QTool) displaying real-time ePRO data to clinicians in the electronic patient record (EPR) at Leeds Teaching Hospitals NHS Trust (LTHT). Hierarchical algorithms were developed corresponding to Common Terminology Criteria for Adverse Events (CTCAE) grading using the QTool question dependency function. Patient advocates (N = 9), patients (N = 13) and staff (N = 19) usability tested the system reporting combinations of AE. Results: The eRAPID system allows patients to report AE from home on PC, tablet or any web enabled device securely during treatment. The system generates immediate self-management advice for low or moderate AE and for severe AE advice to contact the hospital immediately. Clinicians can view patient AE data in the EPR and receive email notifications when patients report severe AE. Conclusions: Evaluation of the system in a Randomised Controlled Trial in breast, gynaecological and colorectal cancer patients undergoing systemic therapy is currently underway. To adapt eRAPID for different treatment groups pilot studies are being undertaken with patients receiving pelvic radiotherapy and upper gastrointestinal surgery.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017, The Author. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. This is a pre-copyedited, author-produced PDF of an article accepted for publication in the Annals of Oncology following peer review. The version of record, 'Holch, P, Warrington, L, Bamforth, L et al (2017) Development of an integrated electronic platform for patient self-report and management of adverse events during cancer treatment. Annals of Oncology. mdx317,' is available online at: https://doi.org/10.1093/annonc/mdx317 |
Keywords: | Adverse Events, CTCAE, Electronic Patient Reported Outcomes, Electronic Patient Records, Integration, Patient self-management |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Computing (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Healthcare (Leeds) > Nursing Adult (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) > Clinical Cancer Research (Leeds) |
Funding Information: | Funder Grant number NIHR National Inst Health Research RP-PG-0611-20008 |
Depositing User: | Symplectic Publications |
Date Deposited: | 06 Jul 2017 11:22 |
Last Modified: | 24 Nov 2020 17:26 |
Status: | Published |
Publisher: | Oxford Univerisity Press |
Identification Number: | 10.1093/annonc/mdx317 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:118717 |