Pedrazzoli, D., Boccia, D., Dodd, P.J. orcid.org/0000-0001-5825-9347 et al. (6 more authors) (2017) Modelling the social and structural determinants of tuberculosis: opportunities and challenges. International Journal of Tuberculosis and Lung Disease, 21 (9). pp. 957-964. ISSN 1027-3719
Abstract
Introduction
Despite the close link between tuberculosis (TB) and poverty, most mathematical models of TB have not addressed underlying social and structural determinants (SD). In this paper, we review studies employing mathematical modelling to evaluate the epidemiological impact of SD of TB.
Methods
We systematically searched PubMed and personal libraries to identify eligible papers. We extracted data on modelling techniques employed, research question, type of SDs modelled, and setting.
Results
From 232 records identified, we included eight papers published between 2008 and 2015; six employed population-based dynamic TB transmission models and two non-dynamic analytic models. Seven studies focused on proximal TB determinants (four on nutritional status, one on wealth, one on indoor air pollution, and one examined overcrowding, socioeconomic and nutritional status), and one focused on macroeconomic influences.
Conclusions
Few modelling studies have attempted to evaluate SD of TB, resulting in key knowledge gaps. Despite challenges of modelling such a complex system, models must broaden their scope to remain useful for policy making. Given the inter-sectoral nature of the interrelations between SD and TB outcomes, this work will require multi-disciplinary collaborations. A useful starting point would be to focus on developing relatively simple models that can strengthen our knowledge regarding the potential effect of SD on TB outcomes.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017 Pedrazzoli et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | mathematical modelling; social determinants; tuberculosis |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 05 Jul 2017 11:54 |
Last Modified: | 24 Sep 2024 09:55 |
Status: | Published |
Publisher: | International Union Against Tuberculosis and Lung Disease |
Refereed: | Yes |
Identification Number: | 10.5588/ijtld.16.0906 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:118441 |