Li, R., Boyd-Moss, M., Long, B. et al. (6 more authors) (2017) Facile control over the supramolecular ordering of self-assembled peptide scaffolds by simultaneous assembly with a polysacharride. Scientific Reports, 7 (1). 4797. ISSN 2045-2322
Abstract
Enabling control over macromolecular ordering and the spatial distribution of structures formed via the mechanisms of molecular self-assembly is a challenge that could yield a range of new functional materials. Here, we show that via co-assembly with a highly charged polysaccharide, fucoidan, the microscale ordering of Fmoc-FRGDF peptide fibrils and subsequent mechanical properties of the resultant hydrogel can be effectively manipulated without disruption to the nanofibrillar structure of the assembly.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2017. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
Keywords: | Biomaterials; Self-assembly; Tissue engineering and regenerative medicine |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Physics and Astronomy (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 08 Jun 2017 14:30 |
Last Modified: | 20 Oct 2023 11:08 |
Status: | Published |
Publisher: | Nature Publishing Group |
Refereed: | Yes |
Identification Number: | 10.1038/s41598-017-04643-3 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:117245 |