Taccola, S, Pensabene, V orcid.org/0000-0002-3352-8202, Fujie, T et al. (3 more authors) (2017) On the injectability of free-standing magnetic nanofilms. Biomedical Microdevices, 19. 51. ISSN 1387-2176
Abstract
Free standing films with sub-micrometric thickness, composed of soft polymers and functional nanostructures are promising candidates for many potential applications in the biomedical field, such as reduced port abdominal surgery. In this work, freely suspended poly(L lactic acid) nanofilms with controlled morphology embedding superparamagnetic iron oxide nanoparticles were fabricated by spin coating deposition. The mechanical properties of magnetic nanofilms were investigated by Strain-Induced Elastic Buckling Instability for Mechanical Measurements (SIEBIMM) test. Our results show that these freely suspended nanocomposite nanofilms are highly flexible and deformable, with Young’s moduli of few GPa. Since they can be handled in liquid with syringes, a quantitative description of the nanofilms behavior during the manipulation with clinically applicable needles has been also provided. These magnetic nanofilms, remotely controllable by external electromagnetic fields, have potential applications in minimally invasive surgery as injectable nanopatches on inner organs wall.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © Springer Science+Business Media New York 2017. This is an author produced version of a paper published in Biomedical Microdevices. The final publication is available at Springer via https://doi.org/10.1007/s10544-017-0192-1. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | nanofilm; nanopatch; injectability; magnetic nanocomposite; SIEBIMM; minimally invasive surgery |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Electronic & Electrical Engineering (Leeds) > Pollard Institute (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 23 May 2017 15:43 |
Last Modified: | 02 Jun 2018 00:38 |
Status: | Published |
Publisher: | Springer Verlag |
Identification Number: | 10.1007/s10544-017-0192-1 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:116749 |