Hoffman, E. and Winder, S.J. orcid.org/0000-0001-7634-8415 (2016) A modified wire hanging apparatus for small animal muscle function testing. PLoS Currents. ISSN 2157-3999
Abstract
Wire hang tests are simple and cheap methods to assess muscle performance in small rodents, but do not always yield consistent results. We describe a simple wire hang apparatus that comprises a continuous rolling loop. Wire hang times measured using the rolling wire provide consistent and reliable data that more accurately reflect the output of a continuous physical effort. As such data obtained in mice using a rolling wire are more representative of the physical changes in the mouse muscle and less susceptible to individual mouse behaviour and differences in animal handling.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016 The Author(s). Available under Creative Commons Attribution License. |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield) > Department of Biomedical Science (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 16 May 2017 13:49 |
Last Modified: | 27 Jul 2020 11:06 |
Published Version: | https://doi.org/10.1371/currents.md.1e2bec4e78697b... |
Status: | Published |
Publisher: | Public Library of Science |
Refereed: | Yes |
Identification Number: | 10.1371/currents.md.1e2bec4e78697b7b0ff80ea25a1d38be |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:116333 |