Adams, H., Baker, M., Hodson, H. et al. (1 more author) (2017) One-pot synthesis of 3-arylaminomaleimides from terminal alkynes and isocyanates. Tetrahedron Letters, 58 (17). pp. 1695-1698. ISSN 0040-4039
Abstract
The reaction of aryl acetylide anions with phenyl isocyanate and subsequent addition of a protonating agent such as ethanol affords good yields of 3-aminomaleimides, formed by the cyclization of one molecule of alkyne with two isocyanates. When the reaction is quenched with water instead, cyclopentadienone imines are formed as the major products.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017 Elsevier. This is an author produced version of a paper subsequently published in Tetrahedron Letters. Uploaded in accordance with the publisher's self-archiving policy. Article available under the terms of the CC-BY-NC-ND licence (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
Keywords: | Acetylide; Alkyne; Isocyanate; Hydantoin; Heterocycle; Maleimide |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 18 Apr 2017 15:02 |
Last Modified: | 12 Mar 2018 01:39 |
Published Version: | https://doi.org/10.1016/j.tetlet.2017.03.050 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.tetlet.2017.03.050 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:115097 |
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