Bebb, O orcid.org/0000-0003-0974-9109, Smith, FGD, Clegg, A orcid.org/0000-0001-5972-1097 et al. (2 more authors) (2018) Frailty and acute coronary syndrome: A structured literature review. European Heart Journal: Acute Cardiovascular Care, 7 (2). pp. 166-175. ISSN 2048-8726
Abstract
The health burden of acute coronary syndrome (ACS) and frailty is high, but the impact of frailty on ACS treatment and outcomes is uncertain. In this structured literature review, we investigated the relationship between frailty, ACS treatment and outcomes. Between 2000 and 2016, we identified only a small number of primary research studies investigating frailty and ACS care (n = 10). Frailty was independently associated with increased mortality following ACS (adjusted all-cause mortality hazard ratios for patients with frailty ranged from 1.54 to 5.39). Older people with frailty were significantly less likely to receive guideline-indicated ACS care, including percutaneous coronary intervention (PCI) (rates ranged from 6.7% to 43.7% vs. from 30.4% to 69.5%). Available data for PCI indicated a gap between treatment recommended by international guidelines and clinical practice. Further research is warranted in order to investigate methods for identifying frailty in the acute setting and opportunities for improving care among older people with frailty presenting with ACS.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017 The European Society of Cardiology. This is an author produced version of a paper published in European Heart Journal: Acute Cardiovascular Care. Reprinted by permission of SAGE Publications. |
Keywords: | Frailty; acute coronary syndrome; ACS; quality of care; mortality |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Health Sciences (Leeds) > Academic Unit of Elderly Care and Rehabilitation (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 04 Apr 2017 09:22 |
Last Modified: | 11 May 2018 08:53 |
Status: | Published |
Publisher: | SAGE Publications |
Identification Number: | 10.1177/2048872617700873 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:114541 |