Morgan, J.L., Walters, S.J. orcid.org/0000-0001-9000-8126, Collins, K. et al. (5 more authors) (2017) What influences healthcare professionals’ treatment preferences for older women with operable breast cancer? An application of the discrete choice experiment. European Journal of Surgical Oncology (EJSO), 43 (7). pp. 1282-1287. ISSN 0748-7983
Abstract
Introduction : Primary endocrine therapy (PET) is used variably in the UK as an alternative to surgery for older women with operable breast cancer. Guidelines state that only patients with “significant comorbidity” or “reduced life expectancy” should be treated this way and age should not be a factor. Methods : A Discrete Choice Experiment (DCE) was used to determine the impact of key variables (patient age, comorbidity, cognition, functional status, cancer stage, cancer biology) on healthcare professionals’ (HCP) treatment preferences for operable breast cancer among older women. Multinomial logistic regression was used to identify associations. Results : 40% (258/641) of questionnaires were returned. Five variables (age, co-morbidity, cognition, functional status and cancer size) independently demonstrated a significant association with treatment preference (p < 0.05). Functional status was omitted from the multi- variable model due to collinearity, with all other variables correlating with a preference for operative treatment over no preference (p < 0.05). Only co-morbidity, cognition and cancer size correlated with a preference for PET over no preference (p < 0.05). Conclusion : The majority of respondents selected treatment in accordance with current guidelines, however in some scenarios, opinion was divided, and age did appear to be an independent factor that HCPs considered when making a treatment decision in this population.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. This is an author produced version of a paper subsequently published in European Journal of Surgical Oncology (EJSO). Uploaded in accordance with the publisher's self-archiving policy. Article available under the terms of the CC-BY-NC-ND licence (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
Keywords: | Breast cancer; Primary endocrine therapy; Surgery; Discrete choice experiment; Older |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology and Metabolism (Sheffield) The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Funding Information: | Funder Grant number NATIONAL INSTITUTE FOR HEALTH RESEARCH UNSPECIFIED |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 22 Mar 2017 15:31 |
Last Modified: | 30 Jun 2023 14:26 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.ejso.2017.01.012 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:113923 |
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Filename: Morgan et al FINAL word version of accepted paper EJSO 2017.pdf
Licence: CC-BY-NC-ND 4.0