Kapaya, H., May, L., Jacques, R. orcid.org/0000-0001-6710-5403 et al. (1 more author) (2017) Sensitivity of postnatal fasting plasma glucose in identifying impaired glucose tolerance in women with gestational diabetes-25 year’s data. Obstetric Medicine, 10 (3). pp. 125-131. ISSN 1753-495X
Abstract
Objective - To assess the uptake of postnatal oral glucose tolerance test and to determine the sensitivity of fasting postnatal blood sugar in predicting 2-h impaired glucose tolerance.
Methods - Retrospective study of 1961 women diagnosed with gestational diabetes mellitus. All women were offered oral glucose tolerance test six weeks post-delivery.
Results - Of 1961 women, 1090 (56%) returned for postpartum oral glucose tolerance test. A fasting plasma glucose of ≥6.1 mmol/l identified only 76 of 167 women with impaired glucose tolerance detected by a 2-h oral glucose tolerance test (sensitivity of 45.5%; 95%CI: 38.1–53.1). We observed a normal fasting glucose but an impaired 2-h glucose tolerance in 91 out of 968 (9.4%) women. Asian ethnicity, admission on special care baby unit and antenatal insulin therapy strongly predicted 2-h impaired postnatal blood glucose levels (P < 0.05).
Conclusion -Although fasting plasma glucose is a convenient method, it lacks sensitivity in identifying women with impaired glucose tolerance postnatally.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
Keywords: | Gestational diabetes; pregnancy; oral glucose tolerance test; impaired glucose tolerance; fasting plasma glucose; diagnosis; screening |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 15 Mar 2017 14:26 |
Last Modified: | 28 Jul 2023 15:17 |
Status: | Published |
Publisher: | SAGE Publications Ltd |
Refereed: | Yes |
Identification Number: | 10.1177/1753495X17702786 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:113453 |