Cox-Nowak, K., Al-Yamani, O., Grant, C.A. et al. (2 more authors) (2017) Poly(n-butyl Methacrylate) with Primary Amine End Groups for Supporting Cell Adhesion and Proliferation of Renal Epithelial Cells. International Journal of Polymeric Materials and Polymeric Biomaterials, 66 (15). pp. 762-767. ISSN 0091-4037
Abstract
Polymer coatings that support epithelial cell culture have been developed. Ozonolysis and subsequent work up of poly(butyl methacrylate-co-butadiene) copolymers is used to form oligomers with carboxylic acid end groups, which are then further reacted with diamines to provide poly(butyl methacrylate)s with primary amine end groups. The polymers are cast as films and used as cell culture substrates for human dermal fibroblasts and human renal epithelial cells. Fibroblast and epithelial cells adhere and proliferate on acid functional materials but on amine functional films epithelial cells show greater viability than fibroblasts.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017 Taylor & Francis. This is an author produced version of a paper subsequently published in International Journal of Polymeric Materials and Polymeric Biomaterials. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | biocoatings; amines; epithelial cells; fibroblast cells |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Materials Science and Engineering (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 15 Feb 2017 12:15 |
Last Modified: | 07 Jul 2023 16:25 |
Status: | Published |
Publisher: | Taylor & Francis |
Refereed: | Yes |
Identification Number: | 10.1080/00914037.2016.1264947 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:112222 |