Zakrzewska, JM, Wu, J orcid.org/0000-0001-6093-599X, Mon Williams, M et al. (2 more authors) (2017) Evaluating the impact of trigeminal neuralgia. Pain, 158 (6). pp. 1166-1174. ISSN 0304-3959
Abstract
Patients with idiopathic trigeminal neuralgia (TN) were categorised into 3 subtypes (n 5 225). Group 1 (n 5 155, 68.9%) had TN
without concomitant pain, group 2 (n532, 14.2%) had TN with intermittent concomitant pain, and group 3 (n539, 16.9%) had TN
with autonomic symptoms. We tested 2 hypotheses: (1) that different pain profiles would be associated with the different groups; (2)
that the severe pain associated with TN would impact negatively on activities of daily living and thereby result in disability as defined
by the World Health Organisation. A different pain profile was found across the groups. We obtained unequivocal evidence that TN
causes disability with up to 45% of patients being absent from usual daily activities 15 days or more in the past 6 months. On the
Hospital Anxiety and Depression Scale, 35.7% patients had mild-to-severe depression and over 50% were anxious. The Pain
Catastrophizing Scale showed that 78% of patients had considerable negative thoughts with scores.20 and a mean score of 36.4.
Prior to referral, only 54% had been prescribed carbamazepine while opioids had been prescribed in 14.6% of the patients. Prior to
referral, over 80% had already been to 1 specialist centre which had not provided appropriate management. Patients with TN report
varied characteristics but all result in some degree of psychosocial disability especially before adequate therapy is attained.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017, International Association for the Study of Pain. This is an author produced version of a paper published in Pain. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Trigeminal neuralgia; Quality of life; Disability; Sociodemographic |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Dentistry (Leeds) > Applied Health and Clinical Translation (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Psychology (Leeds) |
Funding Information: | Funder Grant number Wellcome Trust 086037/B/08/Z |
Depositing User: | Symplectic Publications |
Date Deposited: | 18 Jan 2017 11:32 |
Last Modified: | 06 Dec 2019 17:34 |
Status: | Published |
Publisher: | Lippincott, Williams & Wilkins |
Identification Number: | 10.1097/j.pain.0000000000000853 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:110714 |