Zakrzewska, JM, Wu, J orcid.org/0000-0001-6093-599X, Mon Williams, M et al. (2 more authors) (2017) Evaluating the impact of trigeminal neuralgia. Pain, 158 (6). pp. 1166-1174. ISSN 0304-3959
Abstract
Patients with idiopathic trigeminal neuralgia (TN) were categorised into 3 subtypes (n 5 225). Group 1 (n 5 155, 68.9%) had TN
without concomitant pain, group 2 (n532, 14.2%) had TN with intermittent concomitant pain, and group 3 (n539, 16.9%) had TN
with autonomic symptoms. We tested 2 hypotheses: (1) that different pain profiles would be associated with the different groups; (2)
that the severe pain associated with TN would impact negatively on activities of daily living and thereby result in disability as defined
by the World Health Organisation. A different pain profile was found across the groups. We obtained unequivocal evidence that TN
causes disability with up to 45% of patients being absent from usual daily activities 15 days or more in the past 6 months. On the
Hospital Anxiety and Depression Scale, 35.7% patients had mild-to-severe depression and over 50% were anxious. The Pain
Catastrophizing Scale showed that 78% of patients had considerable negative thoughts with scores.20 and a mean score of 36.4.
Prior to referral, only 54% had been prescribed carbamazepine while opioids had been prescribed in 14.6% of the patients. Prior to
referral, over 80% had already been to 1 specialist centre which had not provided appropriate management. Patients with TN report
varied characteristics but all result in some degree of psychosocial disability especially before adequate therapy is attained.
Metadata
| Item Type: | Article |
|---|---|
| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © 2017, International Association for the Study of Pain. This is an author produced version of a paper published in Pain. Uploaded in accordance with the publisher's self-archiving policy. |
| Keywords: | Trigeminal neuralgia; Quality of life; Disability; Sociodemographic |
| Dates: |
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| Institution: | The University of Leeds |
| Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Dentistry (Leeds) > Applied Health and Clinical Translation (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Psychology (Leeds) |
| Funding Information: | Funder Grant number Wellcome Trust 086037/B/08/Z |
| Depositing User: | Symplectic Publications |
| Date Deposited: | 18 Jan 2017 11:32 |
| Last Modified: | 06 Dec 2019 17:34 |
| Status: | Published |
| Publisher: | Lippincott, Williams & Wilkins |
| Identification Number: | 10.1097/j.pain.0000000000000853 |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:110714 |

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