Mebrahtu, TF, Feltbower, RG orcid.org/0000-0002-1728-9408 and Parslow, RC orcid.org/0000-0002-3945-5294 (2016) Incidence and Burden of Wheezing Disorders, Eczema, and Rhinitis in Children: findings from the Born in Bradford Cohort. Paediatric and Perinatal Epidemiology, 30 (6). pp. 594-602. ISSN 0269-5022
Abstract
Background: Bradford city has high infant mortality and there is a major health concern in the community due to environmental pollution. The aim of the study was to investigate the incidence and burden of wheezing disorders, eczema, and rhinitis in children aged 3–7 years. Methods: It is a prospective cohort study; the participants were 13 734 children from the Born in Bradford cohort. Results: There were a total of 22.1% (95% Confidence Interval (CI) 21.4, 22.8%), 52.4% (95% CI 51.5%, 53.2%), and 19.3% (95% CI 18.6, 19.9%) incidence cases of wheezing disorders, eczema, and rhinitis respectively. A total of 37% (95% CI 36.2%, 37.8%), 19.5% (95% CI 18.9%, 20.2%,) and 5.9% (95% CI 5.5%, 6.3%) of the children were affected by only one, two, and three diseases respectively. Boys to girls incidence rate ratios for wheezing disorders, eczema, and rhinitis was 1.41 (95% CI 1.31, 1.51), 1.02 (95% CI 0.97, 1.07), and 1.18 (95% CI 1.09, 1.28) respectively. The respective incidence rate ratios of Pakistani to White British were 0.94 (95% CI 0.87, 1.02), 1.31 (95% CI 1.24, 1.39), and 2.03 (95% CI 1.83, 2.25) respectively. Conclusion: This study shows that the burden of wheezing disorders, eczema, and rhinitis in this cohort is higher than previously reported in earlier studies. In addition, it indicates that while boys are more likely to suffer from wheezing disorders, rhinitis, and multiple diseases than girls, Pakistani children are more likely to suffer from eczema, rhinitis, and multiple diseases than White British children.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016 John Wiley & Sons Ltd. This is is the peer reviewed version of the following article: This is the peer reviewed version of the following article: Mebrahtu, TF, Feltbower, RG and Parslow, RC (2016) Incidence and Burden of Wheezing Disorders, Eczema, and Rhinitis in Children: findings from the Born in Bradford Cohort. Paediatric and Perinatal Epidemiology, 30 (6). pp. 594-602. ISSN 0269-5022; which has been published in final form at https://doi.org/10.1111/ppe.12310. This article may be used for non-commercial purposes in accordance with the Wiley Terms and Conditions for Self-Archiving. |
Keywords: | Wheezing disorders; eczema; rhinitis |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Genetics, Health and Therapeutics (LIGHT) > Division of Epidemiology & Biostatistics (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 12 Jan 2017 11:49 |
Last Modified: | 10 Aug 2017 08:18 |
Published Version: | https://doi.org/10.1111/ppe.12310 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1111/ppe.12310 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:110448 |