Baker, Daniel Hart orcid.org/0000-0002-0161-443X and Wade, Alexander Robert Patrick orcid.org/0000-0003-4871-2747 (2017) Evidence for an optimal algorithm underlying signal combination in human visual cortex. Cerebral Cortex. pp. 254-264. ISSN 1460-2199
Abstract
How does the cortex combine information from multiple sources? We tested several computational models against data from steady-state EEG experiments in humans, using periodic visual stimuli combined across either retinal location or eye-of-presentation. A model in which signals are raised to an exponent before being summed in both the numerator and the denominator of a gain control nonlinearity gave the best account of the data. This model also predicted the pattern of responses in a range of additional conditions accurately and with no free parameters, as well as predicting responses at harmonic and intermodulation frequencies between 1 and 30Hz. We speculate that this model implements the optimal algorithm for combining multiple noisy inputs, in which responses are proportional to the weighted sum of both inputs. This suggests a novel purpose for cortical gain control: implementing optimal signal combination via mutual inhibition, perhaps explaining its ubiquity as a neural computation.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author 2016. Published by Oxford University Press. |
Keywords: | gain control,signal combination,visual cortex,Kalman filter,Visual Perception/physiology,Humans,Information Storage and Retrieval/methods,Male,Models, Statistical,Evidence-Based Medicine,Neural Inhibition/physiology,Young Adult,Visual Cortex/physiology,Algorithms,Photic Stimulation/methods,Computer Simulation,Evoked Potentials, Visual/physiology,Brain Mapping,Adult,Female,Models, Neurological,Nerve Net/physiology,Synaptic Transmission/physiology |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Psychology (York) |
Funding Information: | Funder Grant number THE ROYAL SOCIETY UNSPECIFIED EUROPEAN COMMISSION PCIG10-GA-2011-303797 |
Depositing User: | Pure (York) |
Date Deposited: | 03 Jan 2017 14:18 |
Last Modified: | 19 Mar 2025 00:07 |
Published Version: | https://doi.org/10.1093/cercor/bhw395 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1093/cercor/bhw395 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:110014 |
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