Alves Costa Pacheco, Ana, Sherwood, James orcid.org/0000-0001-5431-2032, Zhenova, Anna et al. (9 more authors) (2016) Intelligent approach to solvent substitution:the identification of a new class of levoglucosenone derivatives. ChemSusChem. pp. 3503-3512. ISSN 1864-564X
Abstract
With the increasing restriction and control of hazardous solvents, safer alternatives need to be identified. Here a contemporary approach to solvent selection and substitution is presented that offers a more scientific alternative to the simple “like-for-like” exchange. A new family of levoglucosenonederived compounds is proposed, modeled to determine their solvent properties, synthesized, and tested. These new molecules show promise as replacements for polar aprotic solvents that have chronic toxicity issues, such as dichloromethane, nitrobenzene, and N-methylpyrrolidinone. The success of this approach makes it possible for academia and industry to make calculated, intelligent choices for solvent substitution in the future.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2016, Wiley-VCH. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details |
Keywords: | biomass,green chemistry,molecular modeling,solvatochromism,solvent effects |
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 14 Dec 2016 12:28 |
Last Modified: | 25 Jan 2025 00:06 |
Published Version: | https://doi.org/10.1002/cssc.201600795 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1002/cssc.201600795 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:109432 |
Download
Filename: Cygnet_accepted_pre_print.pdf
Description: Cygnet - accepted pre-print