Ceriani, F. orcid.org/0000-0002-5366-341X and Mammano, F. (2012) Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications. Cell Communication and Signaling, 10. 20. ISSN 1478-811X
Abstract
Calcium ions (Ca2+) regulate numerous and diverse aspects of cochlear and vestibular physiology. This review focuses on the Ca2+ control of mechanotransduction and synaptic transmission in sensory hair cells, as well as on Ca2+ signalling in non-sensory cells of the developing cochlea.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © Ceriani and Mammano; licensee BioMed Central Ltd. 2012 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | Hearing; Inner ear; Transducer adaptation; Ca2+ channels; Cadherin 23; Protocadherin 15; Plasma-membrane Ca2+-ATPase; Prestin; Intracellular stores; Calcium release; Mitochondria; Ribbon synapse; Adenosine-5 '-triphosphate; Inositol 1,4,5-trisphosphate; Connexin 26; Connexin 30; Deafness; Mouse models |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield) > Department of Biomedical Science (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 19 Dec 2016 12:14 |
Last Modified: | 19 Dec 2016 12:14 |
Published Version: | http://dx.doi.org/10.1186/1478-811X-10-20 |
Status: | Published |
Publisher: | BioMed Central |
Refereed: | Yes |
Identification Number: | 10.1186/1478-811X-10-20 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:108194 |