Dehghan Marvast, L., Aflatoonian, A., Talebi, A.R. et al. (2 more authors) (2017) Relationship between Chlamydia trachomatis and Mycoplasma genitalium infection and pregnancy rate and outcome in Iranian infertile couples. Andrologia, 49 (9). e12747. ISSN 0303-4569
Abstract
To study the prevalence of C. trachomatis and M. genitalium in a population of infertile couples from Iran and how this relates to tubal factor infertility, pregnancy rate and outcome of pregnancy. Blood, semen and first void urine samples were obtained from 250 infertile couples and 250 fertile women as a control. Infertile couples were followed up after 24 months to determine diagnosis, referral for assisted conception, any pregnancy and pregnancy outcome. Data were analyzed with regard to the results of(i) serological analysis for specific antibodies to C. trachomatis in serum; (ii) the presence of C. trachomatis and M. genitalium DNA in first void urine ; and (iii) in a semen sample of the male partner. Prevalence of C. trachomatis in our study population was comparable to other studies using similar methods and test specimens. No evidence of M. genitalium infection was found. Detection of C. trachomatis in one partner rarely correlated with infection in the other. The risk of tubal factor infertility and the probability of pregnancy and pregnancy outcome were unrelated to the results of serological tests for C. trachomatis antibodies or the presence of C. trachomatis DNA in first void urine of both partners and in a semen sample provided by the male.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016 Blackwell Verlag GmbH. This is an author produced version of a paper subsequently published in Andrologia. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | C. trachomatis; M. genitalium; Infertility; PCR; pregnancy outcome |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology and Metabolism (Sheffield) The University of Sheffield > Sheffield Teaching Hospitals |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 18 Nov 2016 12:16 |
Last Modified: | 15 Mar 2018 14:21 |
Published Version: | https://doi.org/10.1111/and.12747 |
Status: | Published |
Publisher: | Wiley |
Refereed: | Yes |
Identification Number: | 10.1111/and.12747 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:107504 |