Mitchinson, B., Arabzadeh, E., Diamond, M.E. et al. (1 more author) (2008) Spike-timing in primary sensory neurons: a model of somatosensory transduction in the rat. Biological Cybernetics, 98 (3). pp. 185-194. ISSN 0340-1200
Abstract
In previous work, we constructed a simple electro-mechanical model of transduction in the rat mystacial follicle that was able to replicate primary afferent response profiles to a variety of whisker deflection stimuli. Here, we update that model to fit newly available spike-timing response data, and demonstrate that the new model produces appropriate responses to richer stimuli, including pseudo white noise and natural textures, at a spike-timing level of detail. Additionally, we demonstrate reliable distributed encoding of multi-component oscillatory signals. No modifications were necessary to the mechanical model of the physical components of the follicle-sinus complex, supporting its generality. We conclude that this model, and its continued development, will aid the understanding both of somatosensory systems in general, and of physiological results from higher (e.g. thalamocortical) systems by accurately characterising the signals on which they operate.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2007 Springer-Verlag. This is an author produced version of a paper subsequently published in Biological Cybernetics. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | 1st order vibrissa afferents; follicle-sinus complexes; response transformations; structural organization; trigeminal ganglion; active touch; system; mechanoreceptors; cortex; mouse |
Dates: |
|
Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Psychology (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 14 Nov 2016 14:03 |
Last Modified: | 22 Mar 2018 20:51 |
Published Version: | http://dx.doi.org/10.1007/s00422-007-0208-7 |
Status: | Published |
Publisher: | Springer Verlag |
Refereed: | Yes |
Identification Number: | 10.1007/s00422-007-0208-7 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:107045 |