Pountos, I and Giannoudis, PV (2016) Is there a role of coral bone substitutes in bone repair? Injury, 47 (12). pp. 2606-2613. ISSN 0020-1383
Abstract
Xenogeneic bone graft materials are an alternative to autologous bone grafting. Among such implants, coralline-derived bone grafts substitutes have a long track record as safe, biocompatible and osteoconductive graft materials. In this review, we present the available literature surrounding their use with special focus on the commercially available graft materials. Corals thanks to their chemical and structural characteristics similar to those of the human cancellous bone have shown great potential but clinical data presented to date is ambiguous with both positive and negative outcomes reported. Correct formulation and design of the graft to ensure adequate osteo-activity and resorption appears intrinsic to a successful outcome.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2016 Elsevier Ltd. This is an author produced version of a paper published in Injury. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Corals; Mesenchymal stem cells; Scaffold; Bone healing; Growth factors |
Dates: |
|
Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Orthopaedics (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 28 Oct 2016 09:13 |
Last Modified: | 28 Oct 2017 02:37 |
Published Version: | https://doi.org/10.1016/j.injury.2016.10.025 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.injury.2016.10.025 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:106675 |