Wade, R orcid.org/0000-0001-8365-6547, Igali, L and Figus, A (2016) Skin involvement in Dupuytren's disease. The Journal of hand surgery, European volume, 41 (6). pp. 600-608. ISSN 1753-1934
Abstract
Whether the palmar skin has a role in the development, propagation or recurrence of Dupuytren's disease remains unclear. Clinical assessment for skin involvement is difficult and its correlation with histology uncertain. We prospectively biopsied the palmar skin of consecutive patients undergoing single digit fasciectomy (for primary Dupuytren's disease without clinically involved skin) and dermofasciectomy (for clinically involved skin or recurrence) in order to investigate this relationship. We found dermal fibromatosis in 22 of 44 patients (50%) undergoing fasciectomy and 41 of 59 patients (70%) undergoing dermofasciectomy. Dermal fibromatosis appeared to be associated with greater preoperative angular deformity, presence of palmar nodules and occupations involving manual labour. Dermal fibromatosis exists in the absence of clinical features of skin involvement and we hypothesize that the skin may have a greater role in the development and propagation of Dupuytren's disease than previously thought.III.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | (c) 2016, Author(s). This is an author produced version of a paper published in The Journal of hand surgery, European volume. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Dupuytren’s; Disease; Contracture; Fibromatosis; Fasciectomy; Dermofasciectomy; Skin; Graft; Recurrence; Dermis; Dermal; Outcome; Risk |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 03 Nov 2016 11:16 |
Last Modified: | 18 Jan 2018 02:09 |
Published Version: | https://doi.org/10.1177/1753193415601353 |
Status: | Published |
Publisher: | SAGE Publications |
Identification Number: | 10.1177/1753193415601353 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:105541 |