Mackie, AR orcid.org/0000-0002-5681-0593, Rigby, N, Harvey, P et al. (1 more author) (2016) Increasing dietary oat fibre decreases the permeability of intestinal mucus. Journal of Functional Foods, 26. pp. 418-427. ISSN 1756-4646
Abstract
This study investigates the influence of the dietary fibre β-glucan on nutrient composition and mucus permeability. Pigs were fed a standard diet or a diet containing twice the β-glucan content for 3 days (n = 5 per group), followed by the collection of small intestinal mucus and tissue samples. Samples of the consumed diets were subjected to in vitro digestion to determine β-glucan release, nutrient profile and assessment of mucus permeability. In vitro digestion of the diets indicated that 90% of the β-glucan was released in the proximal small intestine. Measurements of intestinal mucus showed a reduction in permeability to 100 nm latex beads and also lipid from the digested enhanced β-glucan diet. The data from this study show for the first time that reducing mass transfer of bile and lipid through the intestinal mucus layer may be one way in which this decrease in bile reabsorption by soluble fibre is enabled.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license(http://creativecommons.org/licenses/by/4.0/). |
Keywords: | Dietary fibre; Beta-glucan; Porcine; Mucus; Permeability; Diffusion |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 03 Oct 2016 15:26 |
Last Modified: | 05 Oct 2017 16:35 |
Published Version: | http://dx.doi.org/10.1016/j.jff.2016.08.018 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.jff.2016.08.018 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:105513 |