Howe, T.E., Khurram, S.A. orcid.org/0000-0002-0378-9380, Hunter, K. orcid.org/0000-0002-7873-0877 et al. (2 more authors) (2017) Accuracy of staging of oral squamous cell carcinoma of the tongue: should incisional biopsy be done before or after magnetic resonance imaging? British Journal of Oral and Maxillofacial Surgery, 55 (3). pp. 298-299. ISSN 0266-4356
Abstract
Accurate staging of oral squamous cell carcinoma (oral SCC) is essential. Some clinicians delay diagnostic biopsy until after magnetic resonance imaging (MRI). We retrospectively studied the clinical records and histopathological databases of 58 patients with SCC of the tongue; 39 had biopsy before MRI and 19 afterwards. In the group who had the biopsy first, eight were up-staged, nine were down-staged, and in 22 the T stage was accurate. In those who had MRI first, the corresponding figures were two, six, and 11, respectively. The time between initial biopsy and excision was significantly longer in the MRI group (43 days), than in the biopsy group (16 days) (p<0.001). Differences in staging between the two groups were not significant. Whether the biopsy was taken before or after MRI does not seem to affect the accuracy of clinical staging, and to delay biopsy until after staging may be unnecessary.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2016 Elsevier. This is an author produced version of a paper subsequently published in British Journal of Oral and Maxillofacial Surgery. Uploaded in accordance with the publisher's self-archiving policy. Article available under the terms of the CC-BY-NC-ND licence (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
Keywords: | MRI; biopsy; cancer staging; oral cancer; oral squamous cell carcinoma; tongue |
Dates: |
|
Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Clinical Dentistry (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 05 Oct 2016 15:05 |
Last Modified: | 26 Sep 2017 00:29 |
Published Version: | http://dx.doi.org/10.1016/j.bjoms.2016.09.004 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.bjoms.2016.09.004 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:105499 |
Download
Filename: Short Communication Manuscript (Resubmit Edit) V5.pdf
Licence: CC-BY-NC-ND 4.0