Farmer, Thomas James orcid.org/0000-0002-1039-7684, Pellis, Alessandro and Guebitz, Georg (2016) On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions. MOLECULES. 1245. pp. 1-11. ISSN 1420-3049
Abstract
Microwave energy (MWe) is, nowadays, widely used as a clean synthesis tool to improve several chemical reactions, such as drug molecule synthesis, carbohydrate conversion and biomass pyrolysis. On the other hand, its exploitation in enzymatic reactions has only been fleetingly investigated and, hence, further study of MWe is required to reach a precise understanding of its potential in this field. Starting from the authors’ experience in clean synthesis and biocatalyzed reactions, this study sheds light on the possibility of using MWe for enhancing enzyme-catalyzed polycondensation reactions and pre-polymer formation. Several systems and set ups were investigated involving bulk and organic media (solution phase) reactions, different enzymatic preparations and various starting bio-based monomers. Results show that MWe enables the biocatalyzed synthesis of polyesters and pre-polymers in a similar way to that reported using conventional heating with an oil bath, but in a few cases, notably bulk phase polycondensations under intense microwave irradiation, MWe leads to a rapid enzyme deactivation.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016, The Author(s). |
Keywords: | CANDIDA-ANTARCTICA,Microwave chemistry,polycondensation,ENZYMATIC CATALYSIS,bio-based polymer,Platform molecules,bio-based monomers,Enzymatic synthesis,Bio-based monomers,Microwave energy,Polycondensation reactions,Candida antarctica lipase B,Bio-based polymers |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Funding Information: | Funder Grant number EPSRC EP/L017393/1 |
Depositing User: | Pure (York) |
Date Deposited: | 22 Sep 2016 09:35 |
Last Modified: | 22 Jan 2025 00:07 |
Published Version: | https://doi.org/10.3390/molecules21091245 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.3390/molecules21091245 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:105047 |
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