Downregulation of Homologous Recombination DNA Repair Genes by HDAC Inhibition in Prostate Cancer Is Mediated through the E2F1 Transcription Factor

Metadata

Item Type:	Article
Authors/Creators:	Kachhap, S.K. Rosmus, N. Collis, S.J. https://orcid.org/0000-0002-7874-1891 Kortenhorst, M.S.Q. Wissing, M.D. Hedayati, M. Shabbeer, S. Mendonca, J. Deangelis, J. Marchionni, L. Lin, J.Q. Hoti, N. Nortier, J.W.R. DeWeese, T.L. Hammers, H. Carducci, M.A.
Copyright, Publisher and Additional Information:	© 2010 Kachhap et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Keywords:	HISTONE DEACETYLASE INHIBITORS; DOUBLE-STRAND BREAKS; TOPOISOMERASE-II; VALPROIC ACID; IN-VITRO; CELL-LINES; EXPRESSION; DAMAGE; COMPLEX; EPIGENOMICS
Dates:	Published: 18 June 2010 Accepted: 25 May 2010
Institution:	The University of Sheffield
Academic Units:	The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology and Metabolism (Sheffield) The University of Sheffield > Sheffield Teaching Hospitals
Depositing User:	Symplectic Sheffield
Date Deposited:	19 Sep 2016 11:24
Last Modified:	19 Sep 2016 11:24
Published Version:	http://dx.doi.org/10.1371/journal.pone.0011208
Status:	Published
Publisher:	Public Library of Science
Refereed:	Yes
Identification Number:	10.1371/journal.pone.0011208
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:104638

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