Di Natali, C, Beccani, M, Obstein, KL et al. (1 more author) (2014) A wireless platform for in vivo measurement of resistance properties of the gastrointestinal tract. Physiological Measurement, 35 (7). pp. 1197-1214. ISSN 0967-3334
Abstract
Active locomotion of wireless capsule endoscopes has the potential to improve the diagnostic yield of this painless technique for the diagnosis of gastrointestinal tract disease. In order to design effective locomotion mechanisms, a quantitative measure of the propelling force required to effectively move a capsule inside the gastrointestinal tract is necessary. In this study, we introduce a novel wireless platform that is able to measure the force opposing capsule motion, without perturbing the physiologic conditions with physical connections to the outside of the gastrointestinal tract. The platform takes advantage of a wireless capsule that is magnetically coupled with an external permanent magnet. A secondary contribution of this manuscript is to present a real-time method to estimate the axial magnetic force acting on a wireless capsule manipulated by an external magnetic field. In addition to the intermagnetic force, the platform provides real-time measurements of the capsule position, velocity, and acceleration. The platform was assessed with benchtop trials within a workspace that extends 15 cm from each side of the external permanent magnet, showing average error in estimating the force and the position of less than 0.1 N and 10 mm, respectively. The platform was also able to estimate the dynamic behavior of a known resistant force with an error of 5.45%. Finally, an in vivo experiment on a porcine colon model validated the feasibility of measuring the resistant force in opposition to magnetic propulsion of a wireless capsule.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2014 Institute of Physics and Engineering in Medicine. This is an author-created, un-copyedited version of an article accepted for publication in Physiological Measurement. The publisher is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at http://dx.doi.org/10.1088/0967-3334/35/7/1197. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | resistance force, intermagnetic force, magnetic force measurement, wireless capsule endoscopy, gastrointestinal endoscopy, colonoscopy, physiology |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Electronic & Electrical Engineering (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 19 Aug 2016 09:43 |
Last Modified: | 20 Jan 2018 20:10 |
Published Version: | http://dx.doi.org/10.1088/0967-3334/35/7/1197 |
Status: | Published |
Publisher: | IOP Publishing |
Identification Number: | 10.1088/0967-3334/35/7/1197 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:103659 |