Kumar, SS, Fraser, S, Scarsbrook, A orcid.org/0000-0002-4243-032X et al. (3 more authors) (2013) Atypical Presentation of Riedel’s Thyroiditis: Multifocal Nodular Fibrosis and Resolution with Levothyroxine. European Thyroid Journal, 1 (4). pp. 259-263. ISSN 2235-0640
Abstract
Background: Riedel’s thyroiditis is characterised by chronic inflammatory invasive fibrosclerosis of the thyroid gland, surrounding structures, and extrathyroidal fibrosis. We present a case of Riedel’s thyroiditis associated with nodular fibrosis of the lungs and liver. Case: A 40-year-old woman presented with a 3-month history of neck swelling, difficulty swallowing and breathlessness on exertion. Core biopsy of the goitre revealed dense fibrous tissue with mixed chronic inflammatory cells. A staging computed tomography scan revealed a large thyroid mass encasing the oesophagus and compressing the trachea, multiple bilateral pulmonary nodules with no evidence of lymphadenopathy, and multiple suspicious nodular lesions in the liver. A thorascopic biopsy of a lung lesion in its entirety revealed a hyalinising lung lesion with no evidence of malignancy. Following the introduction of levothyroxine replacement, symptomatic improvement occurred in parallel with improvements in imaging. Conclusion: To our knowledge, this is the first description of Riedel’s thyroiditis presenting with nodular extrathyroidal fibrosis, and which showed resolution following institution of levothyroxine.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Keywords: | Riedel’s thyroiditis; Nodular extrathyroidal fibrosis Hypothyroidism; Thyroid peroxidase antibodies; Levothyroxine |
Dates: |
|
Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Inst of Biomed & Clin Sciences (LIBACS) (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 24 Aug 2016 14:26 |
Last Modified: | 15 Nov 2016 22:22 |
Published Version: | http://dx.doi.org/10.1159/000345032 |
Status: | Published |
Publisher: | Karger Publishers |
Identification Number: | 10.1159/000345032 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:101975 |