Synthesis of Functionalized Pyridines via a Regioselective Oxazoline Promoted C-H Amidation Reaction.
Maiden, T.M., Swanson, S., Procopiou, P.A. et al. (1 more author)
(2016)
Synthesis of Functionalized Pyridines via a Regioselective Oxazoline Promoted C-H Amidation Reaction.
Organic Letters, 18 (14).
pp. 3434-3437.
ISSN 1523-7060
Abstract
The first Rh-catalyzed C-H amidation of pyridines is reported. The incorporation of a substituent at the C2 position both is crucial to the success of this transformation and provides considerable scope for further elaboration of the resulting products. Among these compounds, 2-chloropyridines allow access to a selection of intermediates including a versatile azaquinazoline scaffold.
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)