Wells, S.E. and Bellantuono, I. orcid.org/0000-0001-9994-6987 (2016) Building for the future: essential infrastructure for rodent ageing studies. Mammalian Genome, 27 (7-8). pp. 440-444. ISSN 0938-8990
Abstract
When planning ageing research using rodent models, the logistics of supply, long term housing and infrastructure provision are important factors to take into consideration. These issues need to be prioritised to ensure they meet the requirements of experiments which potentially will not be completed for several years. Although these issues are not unique to this discipline, the longevity of experiments and indeed the animals, requires a high level of consistency and sustainability to be maintained throughout lengthy periods of time. Moreover, the need to access aged stock or material for more immediate experiments poses many issues for the completion of pilot studies and/or short term intervention studies on older models. In this article, we highlight the increasing demand for ageing research, the resources and infrastructure involved, and the need for large-scale collaborative programmes to advance studies in both a timely and a cost-effective way.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | The Author(s) 2016. This article is published with open access at Springerlink.com |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Human Metabolism (Sheffield) The University of Sheffield > Sheffield Teaching Hospitals |
Funding Information: | Funder Grant number COST OFFICE cost action BM1402 WELLCOME TRUST (THE) 094270/Z/10/Z |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 05 Jul 2016 10:57 |
Last Modified: | 28 Jun 2017 13:45 |
Published Version: | http://dx.doi.org/10.1007/s00335-016-9646-7 |
Status: | Published |
Publisher: | Springer Verlag |
Refereed: | Yes |
Identification Number: | 10.1007/s00335-016-9646-7 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:101608 |