Harrity, J.P., Allen, B. and Connolly, M. (2016) A Pd-Catalyzed Synthesis of Functionalized Piperidines. Chemistry - A European Journal, 22 (37). pp. 13000-13003. ISSN 0947-6539
Abstract
A readily available cyclic carbamate 1 functions as a general precursor to a range of functionalized piperidine products via a new Pd-catalyzed annulation strategy. An asymmetric catalytic variant provides a rapid and efficient means to access these heterocycles with high to excellent levels of enantiocontrol. Finally, these richly functionalized compounds are amenable to further chemoselective elaboration.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an author produced version of a paper subsequently published in Chemistry - A European Journal. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Pd-catalysis; annulation; enantioselective; piperidine |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
Funding Information: | Funder Grant number LEVERHULME TRUST (THE) F/00 118/BV |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 15 Jun 2016 12:29 |
Last Modified: | 08 Jun 2017 00:38 |
Published Version: | http://dx.doi.org/10.1002/chem.201602586 |
Status: | Published |
Publisher: | John Wiley & Sons |
Refereed: | Yes |
Identification Number: | 10.1002/chem.201602586 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:100810 |